Biztalk from your Vista development station can be an interesting and sometimes frustrating experience. Here are some bookmarks to articles that might help with this process.

From Microsoft:
Biztalk configuration or installation because of CAB file issues KB942181
Biztalk does not start correctly under Vista. Set delayed start for the service as it depends on ESS ( Enterprise Single Sign-on ) KB942284
Many tools in BizTalk require elevated permissions so “Run As Administrator”

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From Blogs etc:

Sometimes Biztalk can get out of sync when deploying. It will just randomly skip steps in redeployment leaving your deployment in a random state. Basically, when this happens a manual uninstall of GAC installed assemblies is necessary. 

One way to solve several deployment issues if you are deploying from Visual Studio is to run Visual Studio as an Administrator. Remember, just being logged in as a user in the admin group doesn’t count. You need to physically right click on VS and “Run as Administrator”.

 

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